L.sakei proBio65® has been clinically studied for supplement use and is demonstrated to support skin health
Postbiotics and Probiotics for Skin Health

Support skin from the inside-out
The skin is colonized by a diverse microbiota that helps to protect it from pathogens, maintain its immunity, support nutrient absorption and skin barrier function. While research is ongoing, there is now scientific recognition that the composition of the skin’s microbiome – and disruptions to its microbial balance – directly impact skin health.
Science also shows that a healthy gut microbiota is a key factor associated with skin health – and changes to the gut microbiome’s composition can negatively impact skin health.2
Isolated from traditional kimchi (Korean fermented vegetables), L. sakei proBio65® is a patented natural lactic acid bacteria strain. In its live probiotic form, L. sakei survives in simulated gastric juice and simulated bile after exposure to gastric juice. L. sakei also has a lack of antibiotic resistance.
Since the company is only selling the heat-treated postbiotic form, suggest inserting statement here regarding the postbiotic form.
Probiotic solutions for Skin health
Latilactobacillus sakei proBio65®
5 billion CFU/dose
Indications and benefits
- Soothes skin irritation
- Relieves itchiness
- Promotes skin comfort
- Promotes skin hydration and moisturizes
- Visibly improves skin condition 3,4
Latilactobacillus sakei proBio65® has been clinically studied for topical application as a cosmetic product and is shown to:
- Promote healthy-looking skin
- Visibly improve skin’s appearance
- Hydrate and moisturize the skin
- Condition the skin.5
Strains
- L. sakei
Formats
Capsules, stick packs (dietary supplement use). Creams, lotions (topical, cosmetic use)
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- Byrd AL, Belkaid Y & Segre JA. The human skin microbiome. Nature Reviews Microbiology vol. 16 143–155 (2018).
- Mahmud Md R et al. Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases. Gut Microbes. 2022; 14: 2096995.
- Rather IA, Kim BC, Lew LC, Cha SK, Lee JH, Nam GJ, Majumder R, Lim J, Lim SK, Seo YJ, Park YH. Oral administration of live and dead cells of Lactobacillus sakei Probio65 alleviated atopic dermatitis in children and adolescents: A randomized, double-blind and placebo-controlled study. Probiotics Antimicrob Proteins 2021;13(2):315-326.
- Woo SI, Kim JY, Lee YJ, Kim NS, Hahn YS. Effect of Lactobacillus sakei supplementation in children with atopic eczema-dermatitis syndrome. Ann Allergy Asthma Immunol. 2010 Apr;104(4):343-8.
- Park SB, Im M, Lee Y, Lee JH, Lim J, Park YH, Seo YJ. Effect of emollients containing vegetable-derived lactobacillus in the treatment of atopic dermatitis symptoms: split-body clinical trial. Ann Dermatol. 2014 Apr;26(2):150-5.