Kaneka Probiotics’ Cardio is an IP-protected and patented probiotic formulation developed to improve the metabolism of cholesterol in the blood. Its formulation contains three clinical strains and there have been two published clinical trials (randomized, double-blind, placebo-controlled design).
These specific, triple Lactobacillus plantarum strains showed a robust capability to survive under harsh gastrointestinal tract (GI) conditions, including exposures to acids and bile. In addition, these specific strains were demonstrated to adhere to intestinal epithelial cells. In terms of lipid metabolism, the strains showed a particular ability to produce large amounts of bile salt hydrolase. Bile salts are responsible for recirculating cholesterol systemically. By hydrolyzing the bile-salt molecule, which contains cholesterol, the re-uptake of cholesterol into the body is impacted.