Bacillus coagulans Unique IS-2®

Robust and stable — making it the probiotic for the challenging food and dietary supplement industries.

Check out the clinical studies
People working out together outdoors while taking Unique IS2

Of all probiotic species, the Bacillus species can withstand harsh manufacturing processes

A Unique Probiotic

High Tolerance & Stability

Bacillus coagulans or Lactobacillus sporogenes, as it was earlier known, is a high-temperature tolerant strain that sets it apart from most of the other probiotic strains – it does not need to be refrigerated and is shelf-stable.

Food supplement capsules with Unique IS-2

The Protective Coating Difference

Bacillus coagulans Unique IS-2® is incredibly robust by virtue of it being encased in a hardened shell, which makes it the ideal strain for challenging product development projects. It is a gram-positive, facultative anaerobic, non-pathogenic, spore-forming, lactic acid-producing bacteria.

This probiotic bacteria is able to withstand harsh conditions, like acidic pH in the stomach, and as such is very effective towards stomach disorders and ailments.

See the study results

Cell Wall

Inner Cell

Natural
Spore Coat

Spore-forming cell
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Unique IS-2® is a thoroughly researched probiotic strain with health benefits that span across health and nutrition

Backed by 25 Clinical Studies

Water

Stability of B. coagulans IS2 in water

Sports Drink

Unique IS2 showed 86% stability when tested in electrolyte drinks stored at 28°C for 6 months

Dark & Milk Chocolate

Unique IS2 maintained 100% stability in both dark and milk chocolate

Oats, Pasta, Jelly, & China Grass

Certifications

Bacillus coagulans Unique IS-2® can be mixed with a variety of foods

Food Applications

  • Cake and cookies

    Baked Foods

    Cakes, muffins, and cookies

  • Cake mix

    Dry Powders

    Cake and soup mixes

  • Cereal bowl

    Finished Products

    Granola, protein bars and breakfast cereals

  • Yogurt

    Dairy Products

    Cheese, milk products, ice creams, and yogurts

  • Juice bottle

    Beverages

    Coffee, tea and juices

  • Candy and gummies

    Gummies

    Gummies, candies and confectionery

It’s also available in various forms for ease of use

Nutraceuticals

Unique IS-2® is a highly stable probiotic with a shelf-life of up to 3 years

Superior Stability

  • High Survivability

    Can withstand the harsh environment of stomach acid (low pH) and bile juices to reach the intestine where it colonizes.

  • Highly Resilient

    Can survive the shipping, manufacturing and transportation processes without significant loss and maximum retention of viability.

  • GRAS

    Unique IS-2® is safe for consumption and has a GRAS no objection from US FDA.

  • Superior Viability

    Stable at room temperature, requires no refrigeration.

  • Resistant to a Greater Range of Temperatures

    Can survive a range of temperatures – high boiling to low freezing temperatures. This has wide applications in the food industry.

  • Needs No Microencapsulation

    Makes it a cost effective probiotic which can be incorporated into a wide range of foods.

  • Compatible With

    A variety of formats including gummies and tablets. Also compatible with vitamins, enzymes, electrolytes, proteins and carbohydrates.

  • Certified

    Gluten free, vegan compliant, halal, and kosher.

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Health Benefits

Our modern lifestyle has so many challenges which makes us susceptible to pathogenic bacteria resulting in a disrupted gut microbiome/dysbiosis and a weaker immune system. This is where Bacillus coagulans Unique IS-2® can provide support for normal functions.

Group of people being healthy and happy while doing yoga

Helps Reduce Bacterial Vaginosis

80% (16/20) subjects reported significant reduction in vaginosis symptoms compared to control group (45% only)

Helps Intestinal and Bowel Metabolism in Adults

Significant decrease in pain (0 = higher pain, 7 = lower pain)

Helps Intestinal and Bowel Metabolism in Children

Significant decrease in pain (0 = higher pain, 8 = lower pain)

Helps Support Healthy Liver Function

Positively impacts liver metabolism

Bacillus coagulans UNIQUE IS-2™ is a trademark of Unique Biotech Ltd, Licensed to Kaneka Americas Holding, Inc.