The Year in Probiotics: Top Scientific and Market Developments of 2025

Happy woman with healthy gut

Kaneka Probiotics’ 2025 achievements demonstrate what’s possible when scientific expertise meets a clear focus on real-world health outcomes.

The global probiotics category in 2025 was propelled by science-based innovation across digestive, immune, cognitive, and women’s health applications. As consumer interest in the microbiome evolves, companies that back their products with robust clinical validation are standing out from the crowd.

For Kaneka Probiotics, 2025 was a banner year defined by scientific achievement, regulatory progress, and global recognition. Through its growing KABP® line of proprietary probiotic strains, the company demonstrated significant advancements in multiple areas of health, particularly for women.

Black and white macro shot of strains

Advancing Gut Health Science

Digestive health remains a cornerstone of the probiotic market, but consumers increasingly expect scientific evidence to substantiate benefits. This year, an ex vivo study shed light on the potential mechanism behind Kaneka Probiotics’ KABP® Intensive G.I. blend and its benefits for people with irritable bowel syndrome (IBS).

The study, published in Gut Microbes, suggested that the probiotic blend may restore alterations in gut barrier function in IBS by modulating the expression of specific genes. This research adds to existing clinical evidence supporting the probiotic blend’s role in managing gut discomfort and promoting balanced digestive function.

Regulatory Milestone: GRAS Status for L. plantarum DR7®

Another highlight for Kaneka Probiotics this year was the FDA’s “No Questions” letter confirming Generally Recognized As Safe (GRAS) status for Lactiplantibacillus plantarum DR7®. This recognition underscores the company’s commitment to quality, safety, and transparency.

The DR7® strain has been clinically studied for its ability to support cognitive performance, mood, and stress resilience through the gut-brain axis. GRAS affirmation opens the door for broader applications across functional foods and beverages, expanding opportunities for partners seeking to bring next-generation probiotics to market.

Happy woman

Recognition: 2025 NutraIngredients Awards

Kaneka’s scientific rigor also earned industry recognition this year. The company took home two 2025 NutraIngredients Awards, for KABP® Menopause and KABP® Cardio, recognizing innovations that address key health needs.

KABP® Menopause, in particular, demonstrates how targeted probiotics can help women manage hormonal transitions. The formula’s benefits for vasomotor symptoms and quality of life resonate with the growing demand for microbiome-focused solutions in women’s health. Meanwhile, KABP® Cardio reflects the expanding potential for probiotics to influence metabolic and cardiovascular markers, areas of strong clinical and consumer interest.

Kaneka Team

Supporting Healthy Aging

Kaneka Probiotics’ research also continued to explore the intersection between gut health, mental well-being, and aging. The company published new clinical data on KABP® 50+ (formerly KABP® Mature Immune Defense), demonstrating improvements in both occasional constipation and mental well-being among older adults.

This dual benefit underscores the growing recognition that gut health plays a central role in mood, cognition, and overall vitality. By addressing both digestive comfort and quality of life, KABP® 50+ supports a more holistic approach to healthy aging.

Grandparents and child

Breakthrough in Women’s Vaginal Health

One of the year’s most notable milestones came with the publication of new research on KABP® Vaginal Balance featuring Lactobacillus gasseri KABP®064. According to the authors, the evidence gathered in this study suggested that oral supplementation of the probiotic strain resulted in colonization in the vaginal microbiota, a key indicator of its ability to support urogenital health.

This finding reinforces growing evidence that oral probiotics can provide systemic benefits for women’s wellness. An area of rising consumer and scientific focus, the women’s health category is evolving toward microbiome-targeted solutions like KABP® Vaginal Balance.

Vaginal health

Boosting Immune Health from Early Life

Rounding out an exceptional year, new clinical findings on Kaneka Probiotics’ AB21 blend expanded on prior adult research, highlighting AB21’s role in strengthening immune resilience from early life.

Happy child

Looking Ahead

With growing consumer sophistication, probiotics are moving from general wellness aids to precisely targeted, evidence-backed solutions. Kaneka Probiotics’ 2025 achievements demonstrate what’s possible when scientific expertise meets a clear focus on real-world health outcomes.

A commitment to clinically validated innovation positions Kaneka Probiotics at the forefront of the next generation of probiotics designed to help shape a healthier, more resilient future for all.