KABP® CARDIO, a unique probiotic formula for maintaining cholesterol levels already in the normal range
Benefits
Take Heart
- A clinically validated option
- Support lifestyle intervention with minimal barriers to adherence and compliance
- May help maintain healthy triglyceride levels
- Most extensively researched, first-to-market probiotic combination with three distinct mechanisms to target cholesterol levels
- Works across a range of cholesterol levels to balance and maintain healthy cholesterol levels
- Helps maintain healthy cholesterol levels/total cholesterol/triglycerides already in the normal range
A Specific Probiotic Formula
Lactiplantibacillus plantarum KABP®-011, Lactiplantibacillus plantarum KABP®-012 and Lactiplantibacillus plantarum KABP®-013.
- Genus: Lactiplantibacillus
- Species: Plantarum
- Strains: KABP®-011, KABP®-012, KABP®-013
3 Patented Strains for a Synergistic Effect
These 3 probiotic strains give KANEKA PROBIOTICS CARDIO unique features, including:
Efficacy and tolerability validated by controlled clinical trials.
Benefits may be mediated by enzymes that disrupt the enterohepatic cycle, promoting cholesterol clearance from the body.
Naturally derived & safe: Well established safety profile. Contains three bacterial strains derived from healthy human microflora.
Demonstrated Safety & Benefits in Controlled Clinical Trials
Supporting cardiovascular health
Results after 12 weeks of KANEKA PROBIOTICS CARDIO treatment vs placebo
- Reduction in LDL-C, total cholesterol and triglyceride levels independently of ethnicity, age, gender.
- No reduction in HDL levels.
- Excellent safety profile.
References:
- Fuentes MC, Lajo T, Carrión JM, Cuñé J. A randomized clinical trial evaluating a proprietary mixture of Lactobacillus plantarum strains for lowering cholesterol. Mediterranean Journal of Nutrition and Metabolism. 2016;9(2):125-135.
- Espadaler J, Audivert S, Navarro-Tapia E, Buj D. Demographic and clinical characteristics influencing the effects of a cholesterol-lowering probiotic. Annals of Nutrition and Metabolism. 2019;74(suppl 1):6.
- Mikerji P, Roper JM, Stahl B, et al. Safety evaluation of AB-LIFE® (Lactobacillys plantarum CECT 7527, 7528 and 7529): Antibiotic resistance and 90-day repeated-dose study in rats. Food and Chemical Toxicology. 2016;92:117-128.
Mechanism of action. Research suggests modulation of the Enterohepatic Cycle.
Cholesterol Cycle
- 1
Liver and bile salts
Liver produces bile salts from blood cholesterol.
- 2
Intestine
These bile salts are released into the intestine to facilitate fat absorption.
- 3
Kaneka Probiotics Cardio in action
The bile salt hydrolase (BSH) activity from Kaneka Probiotics Cardio in the ileum may deconjugate bile acids.
- 4.1
Bile acids
A possible mechanism for lower cholesterol levels is that cholesterol is being used to generate new bile salts, replacing the deconjugated bile lost in the feces. Also, cholesterol absorption may be reduced due to lower bile salt levels.
- 4.2
Colon
Deconjugated bile acids may be transformed into secondary bile acids that can bind to TGR5 receptors in brown adipose tissue and muscle which may increase energy expenditure through the consumtion of triglycerides. This is a mechanism by which BSH may help support healthy triglyceride blood levels.
- 4.3
Excretion
A proportion of deconjugated bile acids may precipitate and be excreted in the feces.
How to use it?
- KANEKA PROBIOTICS CARDIO is a once a day probiotic formulation to help maintain healthy cholesterol levels.
- It can be taken alone or with food. For best results, take with prebiotic food.
Our Approach to Maintaining Healthy Cholesterol Levels
Love your heart
There is a clear trend by some doctors encouraging lifestyle strategies for healthy blood lipid control.
A Comprehensive Approach
There is a need for supplement options that can work along with diets low in saturated fat and cholesterol to support healthy levels by reducing endogenous cholesterol production.
KABP® CARDIO, three probiotic strains of human origin, capable of supporting healthy cholesterol and triglycerides levels already in the normal range
Heart & Soul
Research suggests a mechanism of action that involves modulation of the enterohepatic cholesterol cycle.
Recommended use
- Take preferably with a meal
- For best results, consume daily for a minimum period of 3 months
Disclaimer
These statements have not been evaluated by the Food and Administration. These ingredients are not intended to diagnose, treat, cure or prevent any disease.